Let your true self shine through

Patients today don’t want a filler that ‘owns’ them; they want a filler that naturally integrates into their tissue, so that they can retain their identity and express their emotions with confidence.

Thanks to the Belotero® portfolio of fillers, it’s possible to tailor a personal treatment protocol for every patient, so that they can feel empowered, own their age and own their beauty.

  • Product Profile

    Natural Looking Results

    Belotero® is a family of hyaluronic acid dermal fillers with natural tissue integration, enabling your aesthetic practitioner to create subtle, smooth results while respecting the natural contours of your face1. It is a tailored portfolio that can be used to fill wrinkles, restore facial volume and hydrate skin in an holistic approach that respects your individuality2,3,4,5.

  • Mode Of Action

    The Belotero® difference is the combination of Cohesive Polydensified Matrix® (CPM®) technology for natural integration, and specific rheological properties for 3-D flow1,6,7.

    Belotero’s specific manufacturing process known as CPM® technology, results in different densities of HA, creating a combination of high and low density zones. This allows the gel to ‘mimic’ tissue behaviour, to ensure optimal integration of the gel into the surrounding tissue8. For patients this means that Belotero® integrates seamlessly into skin tissue and stays intact for lasting effect6

    Each product within the Belotero® range has been tailored with specific rheological properties, to achieve different outcomes in various tissue layers and areas of the face. COHESIVITY: enables optimal tissue integration and even distribution. ELASTICITY: gives optimal tissue support while respecting the natural mobility of the face. PLASTICITY: allows malleability (model and shape) of the gel, while respecting the anatomical specificities of each patient.

  • The Belotero® Range and Treatment Areas

    A Tailored Treatment Experience

    The Belotero® family of fillers is a complete and tailored portfolio that can be used to fill wrinkles, restore facial volume and hydrate skin in an holistic approach that respects your individuality.

More information

Adverse events should be reported. Reporting forms and information for United Kingdom can be found at Reporting forms and information for Republic of Ireland can be found at Adverse events should also be reported to Merz Pharma UK Ltd at the address above or by email to or on +44 (0) 333 200 4143.


1. Micheels P et al; Effect of Different Crosslinking Technologies on Hyaluronic Behaviour. J Drugs Dermatol 2016; 15 (5): 600-606.
2. Instructions for use Belotero® Volume Lidocaine
3. Instructions for use Belotero® Balance Lidocaine
4. Instructions for use Belotero® Intense Lidocaine
5. Instructions for use Belotero® Soft Lidocaine
6. Micheels P et al; Two Crosslinking Technologies for Superficial Reticular Dermis Injection: A Comparative Ultrasound and Histologic study; J Clin Aestheti Dermatol 2017; 10(1) 29-36.
7. Sundaram & Fagien 2015 Cohesive Polydensified Matirs Hyaluronic Acid for Fine Lines. Plast Recon Surg. 136:149S, 2015
8. Tran C. et al., In vivo bio-integration of three hyaluronic acid fillers in human skin: a histological study – Dermatology, 2014, 228:47-54.