Stay in shape

A youthful face has a clear shape and defined contours. Collagen and elastin keep our skin supple and youthful but these support structures diminish as we age. Skin is no longer able to ‘bounce back’ so easily: instead, it starts to sag and loses definition – especially in the lower face.

Radiesse®plusplus is an injectable filler that contours and defines facial shape1. After your treatment, when you look in the mirror, you should notice an immediate enhancement2. Radiesse®plusplus also stimulates your body’s own natural collagen and elastin so that your skin stays firm and contoured and your aesthetic results are sustained1,2

  • Product Profile

    Improved from within

    Radiesse® restores skin on two levels. It achieves both immediate enhancement and sustained aesthetic improvement of facial shape and contours.1,2

    Radiesse® stimulates the production of collagen and elastin which are important components of our skin (and which start to become depleted over time). These building-blocks are improved in the months after your Radiesse® treatment to allow you to benefit from sustained improvement.2

  • Mode of Action

    Radiesse®plusplus - How it works

    Once injected, Radiesse®plusplus provides immediate volume and correction3 and also continues to work by stimulating the skin to produce its own natural collagen2. Over time, the gel is absorbed and the body metabolizes the CaHA-microspheres, leaving behind only the skin's natural collagen2.

  • Treatment Areas

    Radiesse®plusplus: Contour1 & Define1

    Radiesse®plusplus demonstrates favourable rheological properties to create contours, shape and definition1

    Radiesse®plusplus is ideally suited to support post-injection contours in the treatment of the lower face1

Adverse events should be reported. Reporting forms and information for United Kingdom can be found at Reporting forms and information for Republic of Ireland can be found at Adverse events should also be reported to Merz Pharma UK Ltd at the address above or by email to or on +44 (0) 333 200 4143.


1. Sundaram H, et al. Comparison of the Rheological Properties of Viscosity and Elasticity in Two Categories of Soft Tissue Fillers: Calcium Hydroxylapatite and Hyaluronic Acid, Derm Surg 2010;1076-0512
2. Yutskovskaya Y, et al. A Randomised, Split-Face, Histomorphologic Study Comparing a Volumetric Calcium
3. Instructions for Use (IFU) Radiesse®plusplus